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Gene regulation and genome stability

Every cell in our body contains nearly identical DNA, which must be accurately read (transcribed), copied (replicated), and repaired. Our research focuses on how transcription is controlled to ensure precise gene expression, and how it coordinates with DNA replication and repair in health and disease.

We are a collaborative and enthusiastic team using biochemistry, structural biology (especially cryo-electron microscopy), and other advanced methods to visualize these molecular processes.

News and Updates


April 1, 2026: We are honored to announce that we have received funding from the Shurl and Kay Curci Foundation! This generous support will be key in advancing our research.


April 1, 2026: A warm welcome to our newest graduate students, Ines Ben Makhlouf and Zachary Green! Following their successful rotations, we are thrilled to have them officially join the team.


January 5, 2026: We're excited to kick off the year by welcoming Ines Ben Makhlouf to our team for the winter rotation. Ines is part of our BMB graduate program.


October 1, 2025: Excited to welcome two rotation students for the fall term. Green, Zachary, from our CB&MB program, and Holguin, Manuel J, from BMB program.


Contact

1200 East California Boulevard
Pasadena, California 91125

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Caltech

Curci Foundation