Publications

# corresponding author

1.) Fianu, I#., Ochmann, M., Walshe, J. L., Dybkov, O., Cruz, J. N., Urlaub, H., & Cramer, P#. (2024). Structural basis of Integrator-dependent RNA polymerase II termination. Nature, 629(8010), 219-227. doi:10.1038/s41586-024-07269-4

2.) Kokic, G., Yakoub, G., van den Heuvel, D., Wondergem, A. P., van der Meer, P. J., van der Weegen, Y., Chernev, A., Fianu, I., Fokkens, T. J., Lorenz, S., Urlaub, H., Cramer, P#., Luijsterburg, M. S#. (2024). Structural basis for RNA polymerase II ubiquitylation and inactivation in transcription-coupled repair. Nat Struct Mol Biol. doi:10.1038/s41594-023-01207-0

3.) Fianu, I., Chen, Y., Dienemann, C., Dybkov, O., Linden, A., Urlaub, H., & Cramer, P#. (2021). Structural basis of Integrator-mediated transcription regulation. Science, 374(6569), 883-887. doi:10.1126/science.abk0154

4.) Fianu, I., Dienemann, C., Aibara, S., Schilbach, S., & Cramer, P#. (2021). Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2. Commun Biol, 4(1), 606. doi:10.1038/s42003-021-02088-z

5.) Obeng, E.M., Fianu, I., Danquah, M.K. Multivalent ACE2 engineering—a promising pathway for advanced coronavirus nanomedicine development. Nano today, 101580. doi.org/10.1016/j.nantod.2022.101580

6.) Rotsch, A.H., Li, D., Dupont, M., Krischuns, T., Oberthuer, C., Stelfox, A., Lukarska, M., Fianu, I., Lidschreiber, M., Naffakh#, N., Dienemann, C#., Cusack, S#., Cramer, P#. 2024. Mechanism of Co-Transcriptional Cap-Snatching by Influenza Polymerase. bioRxiv, pp.2024-08.(Under review at Nature)

(7.) Fianu, I and Cramer, P Reconstitution of the Integrator complex and its interaction with transcription elongation complexes. PhD Thesis. dx.doi.org/10.53846/goediss-8866